Human FABP1/L-FABP enzyme-linked immunoassay kit

CAT: EH0257 Datasheet
Specification 96 Test
Sensitivity 44.07 pg/ml (10 μl)
Standard Curve Range 312.50~20000 pg/ml
Standard Curve Gradient 7 Points
Number of Incubations 2
Detectable sample Liquid phase sample of soluble substances. For example: serum, plasma, cell culture supernatant, tissue grinding liquid, etc.
Sample Volume 10 μl
Type Fully Ready-to-Use
Operation Duration 120min
pg/ml O.D. Average Corrected
0.00 0.0081 0.0077 0.0079
312.50 0.0200 0.0204 0.0202 0.0123
625.00 0.0461 0.0453 0.0457 0.0378
1250.00 0.1192 0.1184 0.1188 0.1109
2500.00 0.3383 0.3448 0.3416 0.3337
5000.00 0.8878 0.9526 0.9202 0.9123
10000.00 1.9040 1.9400 1.9220 1.9141
20000.00 2.9330 3.0100 2.9715 2.9636

Precision

Intra-assay Precision Inter-assay Precision
Sample Number S1 S2 S3 S1 S2 S3
22 22 22 6 6 6
Average(pg/ml) 339.4 1791.2 5777.7 422.3 1927.0 6155.4
Standard Deviation 16.5 78.8 264.6 21.2 52.5 175.3
Coefficient of Variation(%) 4.9 4.4 4.6 5.0 2.7 2.8

Intra-assay Precision (Precision within an assay) Three samples of known concentration were tested twenty-two times on one plate to assess intra-assay precision.

Inter-assay Precision (Precision between assays) Three samples of known concentration were tested six times on one plate to assess intra-assay precision.

Spike Recovery

The spike recovery was evaluated by spiking 3 levels of human FABP1/L-FABP into health human serum sample. The un-spiked serum was used as blank in this experiment.
The recovery ranged from 81% to 120% with an overall mean recovery of 95%.

Sample Values

Sample Matrix Sample Evaluated Range (pg/ml) Detectable (%) Mean of Detectable (pg/ml)
serum303224.34-17741.95100.06460.29

Serum/Plasma – Thirty samples from apparently healthy volunteers were evaluated for the presence of human FABP1/L-FABP in this assay. No medical histories were available for the donors. n.d. = non-detectable. Samples measured below the sensitivity are considered to be non-detectable.

Background: FABP1/L-FABP

FABP1, also known as liver FABP (L-FABP, Z-protein and squalene, and sterol-carrier protein [SCP]) is a member of the intracellular FABP family. It is highly expressed in the liver, intestine, kidney, and lung. FABP1 binds free fatty acids, their co-enzyme A derivatives, and may be involved in intracellular lipid transport.

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